Description
Product Characteristics:
Aliases: 2-oxoglutarate-4-dioxygenase subunit alpha-3 antibody, 4-PH alpha-3 antibody, P4ha3 antibody, P4HA3_HUMAN antibody, Procollagen-proline antibody, Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III antibody, Procollagen-proline, 2-oxoglutarate 4-dioxygenase, alpha subunit, isoform 3 antibody, Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3 antibody, Prolyl 4-hydroxylase subunit alpha-3 antibody, Prolyl 4-hydroxylase, alpha polypeptide III antibody, Prolyl 4-hydroxylase, alpha-3 subunit antibody
Target Information: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]